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DTSTAMP:20250804T084122Z
DESCRIPTION:\nSupported by the generosity of the Killam Trusts\, The Neuro'
 s Killam Seminar Series invites outstanding guest speakers whose research 
 is of interest to the scientific community at The Neuro and 91ÉçÇø Univers
 ity.\n\n\nTo attend in person\, register here\n\nTo watch via vimeo\, clic
 k here\n\n\nJohannes Boltze\n\nProfessor of Neuroscience\, University of W
 arwick\, United Kingdom\n\nHost: edith.hamel [at] mcgill.ca (Edith Hamel)
 \n\nAbstract: Ischemic stroke (IS) is caused by a sudden occlusion of a br
 ain-supplying artery. Stroke is frequent due to the wide representation of
  its risk factors\, a leading cause of death and the most frequent reason 
 for permanent disability in adulthood. Despite its immense medical and soc
 io-economic impact\, re-establishing cerebral blood flow by recanalizing t
 he occluded vessel is the only established therapeutic option. However\, r
 ecanalization therapies are limited by narrow time therapeutic windows\, t
 he requirement of specific infrastructure\, and numerous contraindications
 . Cerebroprotective therapies shielding neurons and glia from ischemic dam
 age would be beneficial in IS. Previous research on such approaches has be
 en futile for decades but recent preclinical and clinical developments hav
 e caused a renaissance of cerebroprotective paradigms. The talk will brief
 ly introduce the complex pathophysiology of IS and explain difficulties th
 e field faced during the development of cerebroprotective paradigms in the
  past. It will then introduce the novel key strategy of acute cerebroprote
 ction and will explain why chances for a therapeutic breakthrough are now 
 higher than ever. The main part of the talk will provide detailed insights
  into selected\, currently investigated cerebroprotective approaches for I
 S by providing data from basic science and translational animal experiment
 s. The talk will conclude by providing a brief overview of the recently es
 tablished translational research concept of multicenter preclinical trials
 .\n
DTSTART:20241008T200000Z
DTEND:20241008T210000Z
LOCATION:de Grandpre Communications Centre\, Montreal Neurological Institut
 e\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University
SUMMARY:Killam Seminar Series: Acute Cerebroprotection in Ischemic Stroke
URL:/neuro/channels/event/killam-seminar-series-acute-
 cerebroprotection-ischemic-stroke-358371
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