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UID:20250923T175152EDT-9236Bw3sDJ@132.216.98.100
DTSTAMP:20250923T215152Z
DESCRIPTION:\nSupported by the generosity of the Killam Trusts\, The Neuro'
 s Killam Seminar Series invites outstanding guest speakers whose research 
 is of interest to the scientific community at the MNI and 91ÉçÇř Universit
 y.\n\n\nTo attend in person\, register here\n\nTo watch via vimeo\, click 
 here\n\n\nAlexandre Boutet\, PhD\n\nAssistant Professor\, University of To
 ronto\, Canada\n\nHost: abbas.sadikot [at] mcgill.ca (Abbas Sadikot)\n\nAb
 stract: Deep brain stimulation (DBS) has become a standard of care therapy
  for movement disorders\, particularly Parkinson’s disease\, essential tre
 mor and dystonia\, and is being investigated in psychiatric and cognitive 
 disorders. To date\, more than 244 000 individuals have been implanted wit
 h DBS worldwide. During DBS surgery\, electrodes are inserted into precise
  brain structures\, usually part of the underlying aberrant circuit. The t
 herapeutic effects achieved with DBS hinge upon selective stimulation of t
 he intended structure through accurate and precise delivery of the stimula
 tion—maximizing therapeutic benefits while minimizing spillover onto neigh
 bouring structures that may produce adverse effects. Recent neuroimaging d
 ata have shown that the therapeutic effect of DBS may be better understood
  as a network effect. Thanks to recent advances in MRI safety\, fMRI can n
 ow be used to probe the consequences of stimulation on brain networks. Spe
 cifically\, it can be used to predict optimal DBS stimulation parameters\,
  which could represent an objective biomarker of clinical response. This c
 ould streamline the current empirical process of individually titrating th
 e stimulation\, which is cumbersome for patients and costly for the health
 care system. This may represent a step towards the possibility of autonomo
 us\, closed-loop functional imaging-assisted DBS programming.\n
DTSTART:20240618T200000Z
DTEND:20240618T210000Z
LOCATION:de Grandpre Communications Centre\, Montreal Neurological Institut
 e\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University
SUMMARY:Killam Seminar Series: DBS in the MRI Scanner: From Contra-Indicati
 on to New Method of Optimizing Treatment of Neurological Disease
URL:/neuro/channels/event/killam-seminar-series-dbs-mr
 i-scanner-contra-indication-new-method-optimizing-treatment-neurological-3
 55245
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