BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4//
BEGIN:VEVENT
UID:20250812T085727EDT-5600IwaNiw@132.216.98.100
DTSTAMP:20250812T125727Z
DESCRIPTION:Abstract:\n\n \n\nLenacapavir is a first-in-class\, long-acting
  HIV-1 capsid inhibitor\, and the active pharmaceutical ingredient of Sunl
 enca®. Three different approaches to stereochemical control of a key amine
  building block of lenacapavir were employed for clinical deliveries\, cul
 minating in a zinc catalyzed crystallization-induced dynamic resolution (C
 IDR) strategy. The CIDR process was further refined to improve process eff
 iciency and scalability\, and produces the target amine in 99.9% chiral pu
 rity.\n\n \n\n \n\n \n\n Bio:\n\nSara was born and raised in Saskatchewan\
 , and received a BSc. from the University of Saskatchewan\, completing an 
 honours project in Prof. Dale Ward's group and spending summers working in
  Prof. David Sanders' lab. She joined Prof. Frederick West's group at the 
 University of Alberta\, completing her PhD thesis titled 'Unconventional S
 ubstrates for the Nazarov and Imino-Nazarov Reactions' in 2012. She then j
 oined Prof. Albert Padwa's group as a postdoc developing cascade stitching
  reactions of bis(diazo)compounds. Sara began her professional career as a
  process chemist at Gilead Alberta ULC in 2013\, and has worked on numerou
 s projects at all stages of drug development ranging from pre-clinical thr
 ough approval over the past decade.\n
DTSTART:20240123T180000Z
DTEND:20240123T193000Z
LOCATION:OM 10
SUMMARY:Chemical Society Seminar: Sara Bonderoff-How a Crystallization-Indu
 ced Dynamic Resolution Helped Make Lenacapavir Possible
URL:/chemistry/channels/event/chemical-society-seminar
 -sara-bonderoff-how-crystallization-induced-dynamic-resolution-helped-make
 -354051
END:VEVENT
END:VCALENDAR