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DTSTAMP:20250508T134231Z
DESCRIPTION:Abstract:\n\nEvolution has produced a fascinating array of lipi
 d structures that dictate the function of biological membranes\, and organ
 isms devote considerable energy to the synthesis and maintenance of such c
 ompositions. Our group has been studying some of the most exotic lipids ob
 served to date\, representing a radical departure from the canonical hydro
 carbons that dominate almost all prokaryotic and eukaryotic membranes. Hig
 hly unusual polycyclobutane-containing ladderane phospholipids and macrocy
 clic tetraether lipids have been identified from anaerobic ammonium-oxidiz
 ing bacteria and archaea\, respectively. Our work has developed syntheses 
 of each of these classes of noncanonical membrane lipids\, and material pr
 oduced therefrom has begun to inform us on their natural functions. These 
 natural products have also inspired us to pursue new approaches to ladder-
 type small molecules and materials as well as new methods for the synthesi
 s of cyclobutanes. This includes the discovery of a practical way to produ
 ce cyclobutadiene\, the so-called “Mona Lisa of organic chemistry.” Simila
 r practicality has been achieved in a photochemical process for engaging s
 imple alkenes in cycloadditions that is tolerant of basic nitrogen atoms. 
 This talk will feature discussions of total synthesis\, methodology develo
 pment\, biophysical studies\, and polymer materials.\n\n \n\nBio:\n\nNoah 
 was born in Oakland\, CA but grew up in south central Maine. He attended C
 olumbia University where he was mentored by Professor James Leighton. He o
 btained his Ph.D. with Professor Phil Baran at the Scripps Research Instit
 ute in La Jolla\, CA and was then an NIH postdoctoral fellow with Professo
 r Eric Jacobsen at Harvard University. He joined the chemistry faculty at 
 Stanford University in the fall of 2012 and was promoted to Associate Prof
 essor in 2019. His research is rooted in synthetic organic chemistry\, but
  his group looks for unique opportunities to interface with other fields. 
 Noah is a passionate mentor\, teacher\, and lover of dogs.\n
DTSTART:20231003T170000Z
DTEND:20231003T183000Z
LOCATION:OM 10\, Maass Chemistry Building\, CA\, QC\, Montreal\, H3A 0B8\, 
 801 rue Sherbrooke Ouest
SUMMARY:Chemical Society Seminar: Noah Burns- Lipid Natural Products as Ins
 piration for Total Synthesis\, Materials\, and Methods
URL:/chemistry/channels/event/chemical-society-seminar
 -noah-burns-lipid-natural-products-inspiration-total-synthesis-materials-a
 nd-349243
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