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UID:20250812T160707EDT-2891PFoUX4@132.216.98.100
DTSTAMP:20250812T200707Z
DESCRIPTION:Abstract:\n\nThe ability to design materials that mimic the com
 plexity and functionality of biological systems is a long standing goal of
  nanotechnology\, with applications in medicine\, energy\, and fundamental
  science. Biological molecules such as proteins\, peptides\, and DNA posse
 ss a rich palette of self-assembly motifs and chemical functional diversit
 y\, and are attractive building blocks for the synthesis of such nanostruc
 tures. In this talk\, we will describe research in creating hybrid materia
 ls that incorporate proteins and peptides with DNA nanotechnology to creat
 e cages\, nanofibers\, and 3D crystals with a high degree of programmabili
 ty and nanoscale resolution. Key to these endeavors will be (bio)molecular
  design\, organic chemistry for linking components in a site-specific fash
 ion\, and the tuning of multiple self-assembly 'modes' to create hybrid st
 ructures. Although the talk will focus on the fundamental chemistry and se
 lf-assembly of these systems\, we will also discuss potential applications
  in areas such as targeted cargo delivery\, biomaterials for regenerative 
 medicine\, and synthesis of virus- and antibody-mimetic nanostructures.\n
 \nBio:\n\nNicholas Stephanopoulos was born in Athens\, Greece\, but grew u
 p outside of Boston\, Massachusetts. He obtained his A.B. in chemistry fro
 m Harvard University\, followed by a one-year stint to earn a Master’s in 
 chemical engineering at MIT. He then pursued doctoral studies at the Unive
 rsity of California\, Berkeley\, working with Prof. Matthew Francis. His r
 esearch focused on using site-specific bioconjugation chemistry to modify 
 viral capsid nano-scaffolds\, in order to create materials for energy\, bi
 omedicine\, and nanotechnology. After earning his PhD in 2010\, he went to
  Northwestern University for postdoctoral studies\, supported by both NIH 
 Ruth Kirschtein and International Institute for Nanotechnology fellowships
 \, working with Prof. Samuel Stupp on self-assembling peptide nanomaterial
 s and their applications to regenerative medicine.\n\n\n	At both Berkeley a
 nd Northwestern\, Prof. Stephanopoulos became interested in integrating pr
 oteins and peptides with DNA nanotechnology. In 2015\, he began his indepe
 ndent career at Arizona State University\, with a goal to merge these mole
 cules into a new class of hybrid nanomaterials\, with applications across 
 a range of fields. He is currently an assistant professor in the School of
  Molecular Sciences and the Biodesign Institute’s Center for Molecular Des
 ign and Biomimetics\, with affiliate appointments in Biomedical Engineerin
 g and Chemical Engineering. Since coming to ASU\, Prof. Stephanopoulos has
  received a number of accolades\, including the 2016 Air Force (AFOSR) You
 ng Investigator Award\, the 2018 NSF CAREER\, and the 2018 NIH Director's 
 New Innovator Award.\n
DTSTART:20191001T170000Z
DTEND:20191001T183000Z
LOCATION:Room 10\, Maass Chemistry Building\, CA\, QC\, Montreal\, H3A 0B8\
 , 801 rue Sherbrooke Ouest
SUMMARY:Chemical Society Seminar: Nicholas Stephanopolous - Hybrid self-ass
 embled nanomaterials from proteins\, peptides\, and DNA
URL:/chemistry/channels/event/chemical-society-seminar
 -nicholas-stephanopolous-hybrid-self-assembled-nanomaterials-proteins-2995
 22
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